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Pharmacology Q&A for Nclex

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Walter, teenage patient is admitted to the hospital because of acetaminophen (Tylenol) overdose. Overdoses of acetaminophen can precipitate life-threatening abnormalities in which of the following organs?
a.    Lungs
b.    Liver
c.    Kidney
d.    Adrenal Glands
2.    A contraindication for topical corticosteroid usage in a male patient with atopic dermatitis (eczema) is:
a.    Parasite infection.
b.    Viral infection.
c.    Bacterial infection.
d.    Spirochete infection.

3.    In infants and children, the side effects of first generation over-the-counter (OTC) antihistamines, such as diphenhydramine (Benadryl) and hydroxyzine (Atarax) include:
a.    Reye’s syndrome.
b.    Cholinergic effects.
c.    Paradoxical CNS stimulation.
d.    Nausea and diarrhea.
4.    Reye’s syndrome, a potentially fatal illness associated with liver failure and encephalopathy is associated with the administration of which over-the-counter (OTC) medication?
a.    acetaminophen (Tylenol)
b.    ibuprofen (Motrin)
c.    aspirin
d.    brompheniramine/psudoephedrine (Dimetapp)
5.    The nurse is aware that the patients who are allergic to intravenous contrast media are usually also allergic to which of the following products?
a.    Eggs
b.    Shellfish
c.    Soy
d.    acidic fruits
6.    A 13-month-old child recently arrived in the United States from a foreign country with his parents and needs childhood immunizations. His mother reports that he is allergic to eggs. Upon further questioning, you determine that the allergy to eggs is anaphylaxis. Which of the following vaccines should he not receive?
a.    Hepatitis B
b.    inactivated polio
c.    diphtheria, acellular pertussis, tetanus (DTaP)
d.    mumps, measles, rubella (MMR)
7.    The cell and Coombs classification system categorizes allergic reactions and is useful in describing and classifying patient reactions to drugs. Type I reactions are immediate hypersensitivity reactions and are mediated by:
a.    immunoglobulin E (IgE).
b.    immunoglobulin G (IgG).
c.    immunoglobulin A (IgA).
d.    immunoglobulin M (IgM).
8.    Drugs can cause adverse events in a patient. Bone marrow toxicity is one of the most frequent types of drug-induced toxicity. The most serious form of bone marrow toxicity is:
a.    aplastic anemia.
b.    thrombocytosis.
c.    leukocytosis.
d.    granulocytosis.
9.    Serious adverse effects of oral contraceptives include:
a.    Increase in skin oil followed by acne.
b.    Headache and dizziness.
c.    Early or mid-cycle bleeding.
d.    Thromboembolic complications.
10.    The most serious adverse effect of Alprostadil (Prostin VR pediatric injection) administration in neonates is:
a.    Apnea.
b.    Bleeding tendencies.
c.    Hypotension.
d.    Pyrexia.
11.    Mandy, a patient calls the clinic today because he is taking atrovastatin (Lipitor) to treat his high cholesterol and is having pain in both of his legs. You instruct him to:
a.    Stop taking the drug and make an appointment to be seen next week.
b.    Continue taking the drug and make an appointment to be seen next week.
c.    Stop taking the drug and come to the clinic to be seen today.
d.    Walk for at least 30 minutes and call if symptoms continue.
12.    Which of the following adverse effects is associated with levothyroxine (Synthroid) therapy?
a.    Tachycardia
b.    Bradycardia
c.    Hypotension
d.    Constipation
13.    Which of the following adverse effects is specific to the biguanide diabetic drug metformin (Glucophage) therapy?
a.    Hypoglycemia
b.    GI distress
c.    Lactic acidosis
d.    Somulence
14.    The most serious adverse effect of tricyclic antidepressant (TCA) overdose is:
a.    Seizures.
b.    Hyperpyrexia.
c.    Metabolic acidosis.
d.    Cardiac arrhythmias.
15.    The nurse is aware that the following solutions is routinely used to flush an IV device before and after the administration of blood to a patient is:
a.    0.9 percent sodium chloride
b.    5 percent dextrose in water solution
c.    Sterile water
d.    Heparin sodium
16.    Cris asks the nurse whether all donor blood products are cross-matched with the recipient to prevent a transfusion reaction. Which of the following always require cross-matching?
a.    packed red blood cells
b.    platelets
c.    plasma
d.    granulocytes
17.   A month after receiving a blood transfusion an immunocompromised male patient develops fever, liver abnormalities, a rash, and diarrhea. The nurse would suspect this patient has:
a.    Nothing related to the blood transfusion.
b.    Graft-versus-host disease (GVHD).
c.    Myelosuppression.
d.    An allergic response to a recent medication.
18.    Jonas comes into the local blood donation center. He says he is here to donate platelets only today. The nurse knows this process is called:
a.    Directed donation.
b.    Autologous donation.
c.    Allogenic donation.
d.    Apheresis.
19.    Nurse Bryan knows that the age group that uses the most units of blood and blood products is:
a.    Premature infants.
b.    Children ages 1-20 years.
c.    Adults ages 21-64 years.
d.    The elderly above age 65 years.
20.    A child is admitted with a serious infection. After two days of antibiotics, he is severely neutropenic. The physician orders granulocyte transfusions for the next four days. The mother asks the nurse why? The nurse responds:
a.    “This is the only treatment left to offer the child.”
b.    “This therapy is fast and reliable in treating infections in children.”
c.    “The physician will have to explain his rationale to you.”
d.    “Granulocyte transfusions replenish the low white blood cells until the body can produce its own.”



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